“In aggregate, the 8 cancers with the fastest-rising incidence (>1% per year) in US adults younger than 50 years (thyroid, anus, kidney, small intestine, colorectum, endometrium, pancreas, and myeloma) have doubled in incidence since 1992, while the aggregate mortality for these cancers has remained flat. Colorectal and endometrial cancer showed a slight rise in mortality; for the others, stable or declining mortality alongside rising diagnoses suggests that greater detection (rather than more disease) accounts for the trend. In some cancers, such as thyroid and kidney cancer, overdiagnosis is well documented. For others, incidental detection or earlier diagnosis may explain the trends. While not among the fastest growing (0.6% per year), breast cancer remains the most common early-onset cancer, and despite rising diagnoses in women younger than 50 years, mortality has decreased by approximately half.”

From JAMA.