“This population-based cohort study in the Basque Country, Spain, examines whether an organized fecal immunochemical test–based screening program was associated with lower colorectal cancer mortality rates from 2004 to 2024…

In this cohort study of 438 134 total all-cause deaths among approximately 2.2 million individuals from 2004 to 2024, biennial FIT-based screening was associated with a 50% decline in age-standardized CRC mortality among adults aged 50 to 69 years, with a significant trend inflection observed 3 years after program initiation.”

From National Center for Biotechnology Information.