“A gene therapy study published recently in the journal Nature Medicine showed promising results in restoring hearing in patients of all ages with genetic hearing loss and congenital deafness. The study involved ten patients aged 1 to 24, all of whom had a genetic form of deafness caused by mutations in the OTOF gene, with hearing improvement observed in all participants…

The therapy was administered via a single injection through the round window membrane, accessed through the trans-mastoid facial recess. This method allowed the gene therapy to target the affected cells precisely without the need for more invasive procedures.

On average, participants experienced an improvement in auditory threshold from 106 decibels—a level indicating profound deafness—to 52 decibels, approaching the level of normal conversation.”

From The Jerusalem Post.