fbpx
01 / 05
Super-Precise CRISPR Tool Enters US Clinical Trials

Nature | Noncommunicable Disease

Super-Precise CRISPR Tool Enters US Clinical Trials

“A high-precision successor to CRISPR genome editing has reached a milestone: the technique, called base editing, has made its US debut in a clinical trial. The trial tests more complex genome edits than those performed in humans so far.

Trial organizers announced on 5 September that the first participant had been treated using immune cells with four base-edited genes, equipping the cells to better target and destroy tumours. The hope is that the approach can tame trial participants’ difficult-to-treat form of leukaemia and serve as a gateway to more complex edits in the future.”

From Nature.

Gavi | Vaccination

Immunization Effort to Avert over 605,000 Cervical Cancer Deaths

“By 2023, Gavi had worked with over 40 countries to provide the HPV vaccine to 23.7 million girls. This massive immunisation effort is projected to avert over 605,000 future deaths from cervical cancer, a testament to the vaccine’s life-saving potential.

In 2023 alone, Gavi-supported countries vaccinated more than 14 million girls – more than the total number vaccinated in the previous decade combined. Thanks to an unprecedented scale-up of vaccine introductions, dedicated investment and expanded access since 2023, Gavi is on track to reach its ambitious goal of protecting 86 million girls with the HPV vaccine by 2025, a milestone that is expected to prevent more than 1.4 million future cervical cancer deaths.”

From Gavi.

World Health Organization | Communicable Disease

Suriname Certified Malaria-Free by WHO

“Today [6/30/25], Suriname became the first country in the Amazon region to receive malaria-free certification from the World Health Organization…

Certification of malaria elimination is granted by WHO when a country has proven, beyond reasonable doubt, that the chain of indigenous transmission has been interrupted nationwide for at least the previous three consecutive years.”

From World Health Organization.

NPR | Drug Use

Drug Deaths Plummet Among Young Americans as Fentanyl Carnage Eases

“‘What we’re seeing is a massive reduction in [fatal] overdose risk, among Gen Z in particular,’ said Nabarun Dasgupta, an addiction researcher at the University of North Carolina. ‘Ages 20 to 29 lowered the risk by 47%, cut it right in half.’

This stunning drop in drug deaths among people in the U.S. is being tracked in data compiled by the Centers for Disease Control and Prevention and other federal agencies.

The latest available records found fentanyl and other drugs killed more than 31,000 people (see chart) under the age of 35 in 2021. By last year, that number had plummeted to roughly 16,690 fatal overdoses, according to provisional CDC data.”

From NPR.