“Computer algorithms have designed highly efficient synthetic enzymes from scratch, with minimal need for tedious hands-on experiments to perfect them. The resulting enzymes catalyze a chemical reaction that no known natural protein can execute, achieving a reaction rate and efficiency similar to naturally occurring enzymes.
The proteins, described on 18 June in Nature, open the door to an era in which bespoke enzymes can be rapidly designed to facilitate a variety of reactions.
‘They’re remarkable,’ says Sílvia Osuna, a computational chemist at the University of Girona in Spain, who was not involved in the study. ‘It’s very hard to computationally design a highly efficient enzyme.'”
From Nature.