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01 / 05
Are We Suffering from a Crisis of Meaning?

Blog Post | Health & Medical Care

Are We Suffering from a Crisis of Meaning?

Better material circumstances may not give life meaning, but they can increase human happiness.

For many decades, critics of economic development argued that rising incomes and greater material abundance did not lead to higher levels of happiness. In 1974, Richard Easterlin from the University of Southern California noted that people in richer countries were not happier than people in poor countries. Subsequent research found that the so-called Easterlin Paradox did not exist. Instead, happiness seems to increase with affluence. Today, a different kind of criticism is gaining round. Happiness may be increasing, the critics of economic development concede, but life in a modern capitalist society is more and more devoid of meaning. What are we to make of this criticism?

Writing in New York Magazine, Andrew Sullivan notes, “As we have slowly and surely attained more progress, we have lost something that undergirds all of it: meaning, cohesion, and a different, deeper kind of happiness than the satiation of all our earthly needs. We’ve forgotten the human flourishing that comes from a common idea of virtue, and a concept of virtue that is based on our nature.” Why, he asks, is there “so much profound discontent, depression, drug abuse, despair, addiction, and loneliness in the most advanced liberal societies”? And, he concludes, “For our civilisation, God is dead… We have no common concept of human flourishing apart from materialism, and therefore we stand alone.”

Let us start by unpacking the difference between happiness and meaning. As Steven Pinker observes in his book Enlightenment Now, “We can make choices that leave us unhappy in the short term but fulfilled over the course of a life, such as raising a child, writing a book, or fighting for a worthy cause… People who lead happy but not necessarily meaningful lives have all their needs satisfied: they are healthy, have enough money, and feel good a lot of the time. People who lead meaningful lives may enjoy none of these boons. Happy people live in the present; those with meaningful lives have a narrative about their past and a plan for the future.”

Happiness, then, isn’t everything. But surely it is better to search for the meaning of life on a full, rather than an empty, stomach. And if it happens that the search for meaning requires fasting, let it be undertaken freely rather than as a compulsion. Economic development increases the scope of life choices that are available to individuals. Whether those individuals make use of the increasing number of opportunities to achieve meaningful ends is up to them.

To complicate matters, meaning is different for everyone. Who is to say that the satisfaction I derive from writing an article about the differences between happiness and meaning is truly meaningful? And is my satisfaction as meaningful as the satisfaction of someone who has just completed an extensive stamp collection?

Unlike happiness, which must, by definition, culminate in ecstasy, meaning is infinite and, therefore, impossible to measure. Sullivan, for example, points to the opioid epidemic in America as an example of “profound discontent, depression, drug abuse, despair, addiction, and loneliness.” It is certainly true, as the Princeton University economists Anne Case and Angus Deaton found, that mortality rates among poor whites in the United States have dramatically increased “due to both rises in the number of ‘deaths of despair’ – death by drugs, alcohol and suicide – and to a slowdown in progress against mortality from heart disease and cancer, the two largest killers in middle age.”

But the two authors also found that “midlife mortality rates continue to fall among all education classes in most of the rich world.” Perhaps the opioid crisis among poor whites, who voted in large numbers for Donald J. Trump in the 2016 U.S. presidential election, should have been of greater concern to previous administrations. But do the growing problems experienced by a particular group of Americans mean that the whole of America is suffering from existential angst? And to what extent is despair of poor white Americans representative of the state of the Western world? The data, alas, is devilishly difficult to come by.

The extent to which the West suffers from the crisis of meaning is less than clear. But, even if the problem is a serious one, is democratic capitalism to blame? Did modern-day liberalism kill God and destroy the “common concept of human flourishing apart from materialism”? No one, after all, prevents individuals from finding God on their own or from obtaining a sense of communal belonging by associating with people who have had a similar spiritual experience.

Likewise, complaints about meaningless pursuit of earthly pleasures (materialism) are a recurrent theme in Western writing. Edward Gibbon, to give just one example, refers to “licentiousness” as an important source of the Decline and Fall of the Roman Empire no fewer than 131 times.

Societies, it seems, go through crises of confidence periodically. As my colleague Jason Kuznicki reminded me, the art (Dadaism) and the literature (F. Scott Fitzgerald’s 1925 novel The Great Gatsby) of the 1920s point to a very deep sense of alienation and the loss of meaning that resulted from the carnage of World War I.

A century later, we may well be, as Sullivan writes, in the midst of a similar episode. If so, history suggests that we shall overcome our civilisational angst once more, though, perhaps, we can do so without the false hope of fascism. Lest it be forgotten, in spite of the horrors of the 20th century, humanity has entered the new millennium more numerous, longer-living, richer, healthier, more educated and, even, more peaceful than ever before.

This first appeared in CapX.

New York Times | Noncommunicable Disease

Patient Begins Newly Approved Sickle Cell Gene Therapy

“On Wednesday, Kendric Cromer, a 12-year-old boy from a suburb of Washington, became the first person in the world with sickle cell disease to begin a commercially approved gene therapy that may cure the condition.

For the estimated 20,000 people with sickle cell in the United States who qualify for the treatment, the start of Kendric’s monthslong medical journey may offer hope. But it also signals the difficulties patients face as they seek a pair of new sickle cell treatments.

For a lucky few, like Kendric, the treatment could make possible lives they have longed for.”

From New York Times.

New Scientist | Health & Medical Care

AI That Determines Risk of Death Helps Save Lives in Hospital Trial

“An artificial intelligence system has proven it can save lives by warning physicians to check on patients whose heart test results indicate a high risk of dying. In a randomised clinical trial with almost 16,000 patients at two hospitals, the AI reduced overall deaths among high-risk patients by 31 per cent.”

From New Scientist.

CNN | Health & Medical Care

Gene Therapy Restores Vision in Patients with Inherited Blindness

“For her entire life, college student Olivia Cook had only a small degree of central vision. It was as if she was watching the world through a straw hole, and in dimly lit places, she could not make out people’s faces, only their silhouettes.

But after receiving an experimental gene-editing treatment to one of her eyes, she now can see things she never saw before.

Cook was born with an inherited retinal disorder that causes blindness, a rare type of eye disorder historically called Leber congenital amaurosis or LCA. A few years ago, she decided to participate in a clinical trial that involved using the gene-editing tool CRISPR to correct the form of inherited blindness that she has…

 This study is the first time that CRISPR has been used in the eyes of living people.

‘The results of this study provide proof of concept that CRISPR-Cas9 gene editing can be used safely and effectively to treat inherited retinal disorders,’ said the study’s first author Dr. Eric Pierce.”

From CNN.

Medical Xpress | Vaccination

New Vaccine Triggers Immune Response to Fight Brain Tumor

“In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain tumor…

Reported May 1 in the journal Cell, the discovery represents a potential new way to recruit the immune system to fight notoriously treatment-resistant cancers using an iteration of mRNA technology and lipid nanoparticles, similar to COVID-19 vaccines, but with two key differences: use of a patient’s own tumor cells to create a personalized vaccine, and a newly engineered complex delivery mechanism within the vaccine.”

From Medical Xpress.