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01 / 05
Ethiopia’s R21 Malaria Vaccine Rollout, a Global First in a Refugee Camp

Doctors Without Borders | Vaccination

Ethiopia’s R21 Malaria Vaccine Rollout, a Global First in a Refugee Camp

“Médecins Sans Frontières (MSF) has completed the first full round of R21 malaria vaccine in Ethiopia, and the first ever completed in a refugee camp globally. In Kule refugee camp, in Gambella region, home to more than 55,000 South Sudanese refugees, 2,100 children under five received their fourth and final dose in November 2025.

‘This is the first time the R21 vaccine has been fully implemented in Ethiopia, and one of the earliest comprehensive rollouts on the African continent. It is also the first full vaccination round carried out in a refugee camp anywhere in the world.’ …

In 2024, malaria transmission in the camp reached the highest level in five years. In response, MSF introduced the R21 vaccine in August as part of an expanded prevention package…

In the period after the first vaccination campaign and other preventive measures, Kule hospital saw close to 50 percent fewer malaria-related deaths in 2025 compared to 2024. Where multiple factors could have had an impact on this significant decrease, it is highly likely the efforts carried out by the medical teams in the camp played a key role in this reduction.”

From Doctors Without Borders.

South China Morning Post | Vaccination

AI-Powered Vaccine Production Line Set to Launch in Beijing

“China has broken ground on what developers say is the country’s first production line for AI-assisted personalised tumour vaccines, raising hopes for millions of new cancer patients every year – a disease that ranks as the nation’s second-leading cause of death.

By October, Beijing-based Likang Life Sciences is expected to complete a new drug research and manufacturing centre in the Beijing Economic and Technological Development Zone, with a total investment of about 110 million yuan (US$16.1 million), according to the district government.

The facility will house cell therapy research laboratories together with a production line of the company’s flagship product, LK101, a personalised cancer vaccine that analyses each patient’s tumour DNA to pinpoint the specific genetic mutations driving the disease. With AI, the company said the procedure could be completed in a day.”

From South China Morning Post.

Gavi | Vaccination

Malaria Vaccine Saves Lives and Reduces Hospitalizations

“The arrival of the RTS,S malaria vaccine was a landmark moment; Ghana, Kenya and Malawi were the first countries in the world to offer it to their populations as part of a pilot project launched in 2019, and the World Health Organization (WHO) recommended it for wider use in 2021.

Early studies indicated that the vaccine had a 13% drop in all-cause mortality, and a comprehensive new study of the last four years of vaccine roll-out published in The Lancet has confirmed this figure. That translates to roughly one in eight deaths prevented…

The study tracked 158 clusters across the three countries, with 79 areas introducing the vaccine in 2019 and 79 serving as comparison areas that received it later. Surveillance was built on a network of more than 26,000 local reporters who notified researchers of child deaths in their communities, followed by home visits to confirm details.

The findings carry particular weight because of how the study was designed. Clusters were randomly assigned, baseline characteristics were balanced, and coverage of other interventions, including bed-nets, routine vaccines and care-seeking for fever, remained similar across implementation and comparison areas throughout the four years.

This means, say the researchers, that the drop in deaths can be  ‘confidently attributed’ to the vaccine itself rather than to other shifts in malaria care.”

From Gavi.

Medical Xpress | Vaccination

mRNA-1010 Superior to Standard-Dose Vaccine for Preventing Flu

“For adults aged 50 years or older, an investigational messenger RNA (mRNA)-based vaccine (mRNA-1010) is superior to standard-dose licensed vaccines for preventing influenza-like illness, according to a study published in the New England Journal of Medicine

Overall, 20,350 participants received mRNA-1010 and 20,353 received the standard-dose comparator. The researchers found that 2.0% and 2.8% of the recipients of mRNA-1010 and the standard-dose comparator, respectively, had RT-PCR-confirmed, protocol-defined influenza-like illness, corresponding to a relative vaccine efficacy of 26.6% and meeting the criteria for noninferiority, superiority, and higher-level superiority. Solicited adverse reactions occurred more often with mRNA-1010 than the standard-dose comparator; they were mainly mild-to-moderate and transient. Overall, 2.2% and 1.9% of recipients of mRNA-1010 and the standard-dose comparator, respectively, had serious adverse events.”

From Medical Xpress.

Gavi | Vaccination

Burkina Faso Celebrates Malaria Vaccine Impact

“Authorities report an unprecedented decline in malaria rates at the national level. At a press briefing in February 2026, Health Minister Robert Kargougou said the total number of recorded malaria cases fell from 10,805,020 in 2024, to 7,329,278 in 2025, a decrease of 32%. Over the same period, deaths fell from 3,523 to 1,979, a drop of 44%. Among children under five, cases declined by 39%, while mortality fell by more than 40%.”

From Gavi.