01 / 05
A New Vaccine May Fix Africa’s “Meningitis Belt”

Telegraph | Vaccination

A New Vaccine May Fix Africa’s “Meningitis Belt”

“For at least a century outbreaks of meningitis have swept across a swathe of Africa running from Senegal to Ethiopia, killing tens of thousands of people every few years.

Desert winds, dust storms, and fragile health systems mean the bacteria that cause the disease can infect people more easily, causing regular epidemics in what’s known as the meningitis belt.

If not treated, this type of bacterial meningitis can kill within hours. One in six who catch it will die and many survivors suffer complications like hearing loss, brain damage and amputations.

Scientists have been battling to break the cycle for decades, but have had only limited success – largely because meningococcal disease is not just caused by one type of bacterium, but many.

But they may now have a new weapon in their arsenal. Along the belt, countries have begun rolling out a five-in-one vaccine that targets the varieties of Neisseria meningitidis bacteria that are responsible for almost all epidemic meningitis in sub-Saharan Africa.

It is the first major breakthrough since the MenAfriVac vaccination was introduced in 2010, which proved highly effective against serogroup A, effectively eliminating the leading cause of meningitis and saving millions of lives.

The new jab, called Men5CV, protects against four more serogroups – C, Y, W and X – and experts are hailing it as the next milestone towards the World Health Organization’s (WHO) goal of eliminating epidemic meningitis by 2030.

The vaccine is already being rolled out in Niger and Nigeria, while Mali, Ghana, Burkina Faso, Chad and Togo all have plans to introduce it in the coming months.”

From Telegraph.

Gavi | Vaccination

Global Mpox Stockpile to Speed Vaccine Access

“A new global mpox vaccine stockpile is set to begin operations later this month, creating a long-term mechanism to help ensure that countries facing mpox outbreaks have rapid and equitable access to vaccines.

Like existing global emergency stockpiles for yellow fever, meningitis, Ebola and cholera vaccines, the mpox stockpile will be available to any country that needs it. However, because supplies are limited and must be distributed equitably, it is designed primarily for emergency outbreak response.

Countries eligible for Gavi support receive stockpiled vaccines free of charge. Wealthier countries can access the stockpile just as quickly, but these countries must subsequently reimburse the cost of the vaccines.”

From Gavi.

World Health Organization | Vaccination

Global Childhood Vaccination Rises but Trails 2019

“In 2025, 90% of infants globally – or nearly 116 million – received at least one dose of a diphtheria, tetanus and pertussis (DTP) vaccine, and 85% – or 110 million – completed the full three-dose series, according to the annual WHO-UNICEF Estimates of National Immunization Coverage (WUENIC) released today.

While both indicators rose by one percentage point from the previous year, global coverage remains one point below 2019 levels – hovering within the same narrow range since 2009.

According to the data, an estimated 13.5 million 'zero-dose' children did not receive a single vaccine in their first year during 2025. While these represent nearly 750 000 fewer children than the previous year, progress is offset by a rising number of children who start the schedule and do not complete it. Most of these children live in countries where national immunization programmes receive support from Gavi, the Vaccine Alliance.”

From World Health Organization.

BBC | Vaccination

Fridge-Free Vaccine Successfully Tested in Humans

“Vaccines that do not need to be kept cool in a fridge have been successfully trialled in patients for the first time, say UK scientists.

Currently, most vaccines need to be refrigerated or frozen – but around half are wasted each year, mainly because they become unusable after getting too hot or too cold.

In the trial, which involved 60 volunteers, company Stablepharma converted a liquid tetanus-diphtheria vaccine into a 'fridge-free' version by keeping it as a dry powder for a year at room temperature before mixing it with water and injecting it.”

From BBC.

Wall Street Journal | Vaccination

FDA Approves First mRNA Flu Vaccine

“The Food and Drug Administration approved Moderna’s mRNA-based flu vaccine Wednesday for adults ages 50 and older, clearing the first shot of its kind after a review process that nearly collapsed in February.

The vaccine, called mFlusiva, uses the same messenger RNA technology as Moderna’s Covid-19 shots. It could reach pharmacies in time for the coming flu season, which typically starts in the fall…

Traditional flu shots are grown in chicken eggs, a process that takes about six months and forces manufacturers to guess months in advance which strains will circulate. Moderna’s mRNA shot can be made in as little as two to three months, meaning it could better match the actual virus once flu season arrives…

In a study of more than 40,000 adults, mFlusiva cut the risk of flu by 26.6% compared with a standard-dose vaccine. That reduction was 47.9% against flu severe enough to send patients to the hospital or urgent care.”

From Wall Street Journal.